Immune dysregulation in minimal change nephropathy

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Immune dysregulation in minimal change nephropathy.

Minimal change nephropathy (MCN) has been associated with a wide variety of abnormalities in the immune response of affected individuals. Many of these may be a consequence of the renal lesion, rather than a cause thereof. This article reviews some of these immunological phenomena and concentrates in particular on the imbalance between type 1 and type 2 cytokine responses, suggesting that there...

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Minimal-change nephropathy in systemic lupus erythematosus.

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IgA nephropathy with minimal change disease.

BACKGROUND AND OBJECTIVES Patients with IgA nephropathy typically present with hematuria and subnephrotic proteinuria. Nephrotic syndrome is uncommon in IgA nephropathy, and when present, it is usually associated with severe histologic features, such as endocapillary proliferation, segmental sclerosis, and crescent formation. Rarely, patients with IgA nephropathy present with nephrotic syndrome...

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Splenic Infarction as Starting Symptom in Minimal Change Nephropathy

Correspondence To the Editor: A 17-year-old Chinese male patient without any medical history presented to The First Affiliated Hospital of Nanchang University. His initial symptoms were abdominal pain and progressive edema. The pain presented initially around umbilical area and then progressed to left upper quadrant of the abdomen. His physical examination revealed that he had mild edema of the...

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Minimal change nephropathy associated with anaplastic carcinoma of bronchus.

Nephrotic syndrome associated with extra-renal malignancy shows a characteristic pattern: carcinoma is most frequently associated with membranous glomerulonephritis and Hodgkin's disease with minimal change nephropathy. We report a patient with minimal change nephropathy in association with anaplastic carcinoma of the bronchus. Strong temporal evidence of a causal relationship is presented. The...

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ژورنال

عنوان ژورنال: Nephrology Dialysis Transplantation

سال: 2003

ISSN: 1460-2385

DOI: 10.1093/ndt/gfg1066